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Concept encyclopediaHormones

Insulin

5 passages
2 authors
2006–2025
Most-cited: Ray Peat

Insulin is a hormone that plays a crucial role in the regulation of blood sugar levels, but its importance has been exaggerated due to the diabetes/insulin industry. Insulin itself accounts for only about 8% of the insulin-like activity in the body, with other factors such as the liver's production of glucose and the body's sensitivity to insulin also playing significant roles .

The degenerative diseases associated with hyperglycemia, commonly referred to as diabetes, are only indirectly related to insulin. The glycemic index of foods, often used as a measure of their effect on blood sugar levels, has little meaning and no constructive use in understanding or treating diabetes .

Research has shown that insulin resistance, rather than insulin deficiency, is a key factor in the development of non-insulin-dependent diabetes mellitus. Insulin resistance is often driven by excessive fat accumulation and oxidation, and can be ameliorated by lowering fat intake, increasing sugar intake, and taking substances such as aspirin and niacinamide .

Studies have also found that insulin resistance is linked to various other conditions, including depression, anxiety, and bipolar disorder. Ameliorating insulin resistance through dietary changes and supplements may be a simple and potentially curative approach to treating these conditions .

In contrast to the conventional view that insulin is essential for glucose metabolism, research has shown that a low-salt diet can increase insulin resistance in healthy subjects, and that mineralocorticoid receptor activation plays a role in insulin resistance .

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