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Concept encyclopediaConditions

Menopause

perimenopause, post-menopause

8 passages
1 author
2006–2021
Most-cited: Ray Peat

Menopause is a condition of increased estrogen exposure and symptoms, primarily resulting from a failure to produce progesterone, which leaves all cells of the body under increased stress, causing them to produce estrogen . This condition is not solely due to the intrinsic aging of the ovaries, but rather a result of changes in the body's hormonal balance .

The mainstream view of menopause as a deficiency of estrogen has been widely accepted, but this idea has been challenged by recent evidence showing that increased estrogen levels are associated with various health problems, including respiratory and circulatory issues, inflammation, and increased mortality .

Progesterone, on the other hand, has been shown to have a balancing effect on estrogen levels, reducing the amount of estrogen in the body and alleviating symptoms . Supplementing with progesterone can be effective in controlling symptoms, but it is essential to monitor thyroid function and nutrition to ensure optimal results .

Menopause is also associated with increased cortisol levels, which can lead to various health problems, including anxiety, insomnia, and depression . The high incidence of depression in both men and women during this period suggests that hormonal changes play a significant role in the development of these symptoms .

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