Progesterone

Progesterone is a hormone that plays a crucial role in both males and females, with its primary function being the regulation of the reproductive cycle in females and the maintenance of overall health in males. It is a protective hormone during pregnancy and has a direct effect on mitochondria, promoting energy production and facilitating thyroid hormone functions. Progesterone also has a normal anesthetic function, which prevents the pain of childbirth when its level is adequate, and it directly quiets nerves, suppressing many of the excitotoxic processes. 6

Progesterone is created in the body through the conversion of cholesterol, and it is not produced from wild yam, despite some products claiming to be derived from it. The human body cannot convert wild yam to progesterone, and unaltered wild yam is toxic in sufficient amounts. 3 Progest-E Complex, a patented oral delivery system for progesterone, contains 10% progesterone content, which is 2850 mg per ounce, and it is designed to work well through the skin and orally. 2

Progesterone has various therapeutic effects, including the suppression of estrogen production, the promotion of thyroid hormone functions, and the elimination of estrogen from tissues. It also has a diuretic effect, which is compatible with the maintenance of blood volume. However, in larger doses, progesterone can have an anti-androgen effect, opposing the effects of testosterone. 6 Progest-E Complex can be used to quickly overcome the negative effects of excess estrogen, cortisol, aldosterone, prolactin, and serotonin, and it can be a strong anesthetic and help with sleep. 5

The cost of testing progesterone levels is relatively low, at around $20, and this has led to some debate about the value of comparing the absorption rates of different progesterone products. 8 Despite this, Progest-E Complex remains a popular choice for those seeking to supplement with progesterone, due to its unique properties and therapeutic effects. 5