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Concept encyclopediaHormones

Thyroid Stimulating Hormone (TSH)

thyroid stimulating hormone, Thyroid Stimulating Hormone, TSH, tsh

TSH itself can produce lipolysis, raising the level of circulating free fatty acids. This suggests that a high level of TSH could sometimes contribute to functional hypothyroidism, because of the antimetabolic effects of the unsaturated fatty acids

8 passages
1 author
2011–2021
Most-cited: Ray Peat

Thyroid Stimulating Hormone (TSH) is an agent of inflammatory processes, directly activating and causing tissue to release inflammatory cytokines and interleukins . This hormone is often used as a diagnostic tool for thyroid function, but its measurement can be misleading due to the stress caused by hypothyroidism and bad diet, which produces stress hormones that lower TSH production . In fact, a stressed, tired, low-energy person will have very low TSH production because of the stress hormones, even if they are hypothyroid . Furthermore, TSH itself can produce lipolysis, raising the level of circulating free fatty acids, which can contribute to functional hypothyroidism .

The medical profession estimates thyroid function based on TSH, but this can be problematic, as TSH rises when we are deficient in actual thyroid function . Additionally, TSH excess can be produced by a deficiency of iodine, as well as by a blockage of the gland's functions, such as from excess iodine . This highlights the limitations of relying solely on TSH measurements for diagnosing thyroid function.

In contrast, actual thyroid hormone can shut down toxic inflammatory processes, and a sufficient level of thyroid hormone can completely turn off the pituitary's production of TSH . This suggests that TSH is not a reliable indicator of thyroid function, and that a more comprehensive approach is needed to diagnose and treat thyroid-related issues.

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